L14I (p.Leu14Ile) variant of CYP1A2 (Cytochrome P450 1A2)
L14I (p.Leu14Ile) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
L14I (p.Leu14Ile) variant details
- p.Leu14Ile
- gnomAD 15-74749778-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.11
- CADD 11.90
- PolyPhen-2 0.35
- SIFT 0.59
- Population evidence available
- Structural context available
- Literature evidence available