K59R (p.Lys59Arg) variant of CYP1A2 (Cytochrome P450 1A2)
K59R (p.Lys59Arg) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
K59R (p.Lys59Arg) variant details
- p.Lys59Arg
- TOPMed rs1177351603
- gnomAD rs1177351603
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.13
- CADD 20.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available