K37R (p.Lys37Arg) variant of CYP1A2 (Cytochrome P450 1A2)
K37R (p.Lys37Arg) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
K37R (p.Lys37Arg) variant details
- p.Lys37Arg
- ExAC rs751602658
- TOPMed rs751602658
- gnomAD rs751602658
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.05
- CADD 20.70
- PolyPhen-2 0.05
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 7.3e-05)
- Structural context available