K37I (p.Lys37Ile) variant of CYP1A2 (Cytochrome P450 1A2)
K37I (p.Lys37Ile) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
K37I (p.Lys37Ile) variant details
- p.Lys37Ile
- ExAC rs751602658
- TOPMed rs751602658
- gnomAD rs751602658
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.31
- CADD 25.10
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available