I20M (p.Ile20Met) variant of CYP1A2 (Cytochrome P450 1A2)
I20M (p.Ile20Met) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
I20M (p.Ile20Met) variant details
- p.Ile20Met
- ExAC rs773045980
- TOPMed rs773045980
- gnomAD rs773045980
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.19
- CADD 23.00
- PolyPhen-2 0.71
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 4.7e-05)
- Structural context available