G52R (p.Gly52Arg) variant of CYP1A2 (Cytochrome P450 1A2)
G52R (p.Gly52Arg) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
G52R (p.Gly52Arg) variant details
- p.Gly52Arg
- ESP rs376605220
- ExAC rs376605220
- TOPMed rs376605220
- gnomAD rs376605220
- Missense
- Variant Prioritization Score for Impact Estimate 0.754
- REVEL 0.93
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available