G47S (p.Gly47Ser) variant of CYP1A2 (Cytochrome P450 1A2)
G47S (p.Gly47Ser) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G47S (p.Gly47Ser) variant details
- p.Gly47Ser
- gnomAD rs939000746
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.08
- CADD 14.40
- PolyPhen-2 0.06
- SIFT 0.48
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available