F25W (p.Phe25Trp) variant of CYP1A2 (Cytochrome P450 1A2)
F25W (p.Phe25Trp) in CYP1A2 (Cytochrome P450 1A2) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
F25W (p.Phe25Trp) variant details
- p.Phe25Trp
- gnomAD 15-74749811-TTCTG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.315
- CADD 24.10
- Population evidence available
- Structural context available
- Literature evidence available