F25S (p.Phe25Ser) variant of CYP1A2 (Cytochrome P450 1A2)
F25S (p.Phe25Ser) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
F25S (p.Phe25Ser) variant details
- p.Phe25Ser
- ESP rs142454118
- ExAC rs142454118
- TOPMed rs142454118
- gnomAD rs142454118
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.48
- CADD 24.00
- PolyPhen-2 0.84
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available