F25L (p.Phe25Leu) variant of CYP1A2 (Cytochrome P450 1A2)
F25L (p.Phe25Leu) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
F25L (p.Phe25Leu) variant details
- p.Phe25Leu
- gnomAD 15-74749813-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.11
- CADD 12.10
- PolyPhen-2 0.04
- SIFT 0.43
- Population evidence available
- Structural context available
- Literature evidence available