F25C (p.Phe25Cys) variant of CYP1A2 (Cytochrome P450 1A2)
F25C (p.Phe25Cys) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
F25C (p.Phe25Cys) variant details
- p.Phe25Cys
- ESP rs142454118
- ExAC rs142454118
- TOPMed rs142454118
- gnomAD rs142454118
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.34
- CADD 23.90
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available