F21C (p.Phe21Cys) variant of CYP1A2 (Cytochrome P450 1A2)
F21C (p.Phe21Cys) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
F21C (p.Phe21Cys) variant details
- p.Phe21Cys
- gnomAD 15-74749800-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.54
- REVEL 0.55
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available