C22Y (p.Cys22Tyr) variant of CYP1A2 (Cytochrome P450 1A2)
C22Y (p.Cys22Tyr) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
C22Y (p.Cys22Tyr) variant details
- p.Cys22Tyr
- gnomAD rs1330830770
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.18
- CADD 21.80
- PolyPhen-2 0.16
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available