C22F (p.Cys22Phe) variant of CYP1A2 (Cytochrome P450 1A2)
C22F (p.Cys22Phe) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
C22F (p.Cys22Phe) variant details
- p.Cys22Phe
- gnomAD 15-74749803-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.16
- CADD 21.90
- PolyPhen-2 0.16
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available