A64T (p.Ala64Thr) variant of CYP1A2 (Cytochrome P450 1A2)
A64T (p.Ala64Thr) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A64T (p.Ala64Thr) variant details
- p.Ala64Thr
- ExAC rs753312654
- TOPMed rs753312654
- gnomAD rs753312654
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.10
- CADD 14.40
- PolyPhen-2 0.14
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available