A64P (p.Ala64Pro) variant of CYP1A2 (Cytochrome P450 1A2)
A64P (p.Ala64Pro) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
A64P (p.Ala64Pro) variant details
- p.Ala64Pro
- gnomAD 15-74749928-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.43
- CADD 23.70
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available