A19V (p.Ala19Val) variant of CYP1A2 (Cytochrome P450 1A2)
A19V (p.Ala19Val) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
A19V (p.Ala19Val) variant details
- p.Ala19Val
- ExAC rs771691950
- gnomAD rs771691950
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.07
- CADD 3.89
- PolyPhen-2 0.01
- SIFT 0.82
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available