A17T (p.Ala17Thr) variant of CYP1A2 (Cytochrome P450 1A2)
A17T (p.Ala17Thr) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
A17T (p.Ala17Thr) variant details
- p.Ala17Thr
- gnomAD 15-74749787-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.14
- CADD 22.90
- PolyPhen-2 0.07
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available