A11T (p.Ala11Thr) variant of CYP1A2 (Cytochrome P450 1A2)
A11T (p.Ala11Thr) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
A11T (p.Ala11Thr) variant details
- p.Ala11Thr
- gnomAD 15-74749769-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.19
- CADD 12.20
- PolyPhen-2 0.60
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available