A11S (p.Ala11Ser) variant of CYP1A2 (Cytochrome P450 1A2)
A11S (p.Ala11Ser) in CYP1A2 (Cytochrome P450 1A2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
A11S (p.Ala11Ser) variant details
- p.Ala11Ser
- gnomAD rs1471159041
- Missense
- Variant Prioritization Score for Impact Estimate 0.0936
- REVEL 0.08
- CADD 7.51
- PolyPhen-2 0.12
- SIFT 0.20
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available