Y11C (p.Tyr11Cys) variant of CYP19A1 (Aromatase)
Y11C (p.Tyr11Cys) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
Y11C (p.Tyr11Cys) variant details
- p.Tyr11Cys
- TOPMed rs981890008
- Missense
- Variant Prioritization Score for Impact Estimate 0.42
- REVEL 0.45
- CADD 22.30
- PolyPhen-2 0.68
- SIFT 0.08
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available