P22S (p.Pro22Ser) variant of CYP19A1 (Aromatase)
P22S (p.Pro22Ser) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P22S (p.Pro22Ser) variant details
- p.Pro22Ser
- ExAC rs747161974
- TOPMed rs747161974
- gnomAD rs747161974
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.07
- CADD 13.70
- PolyPhen-2 0.01
- SIFT 0.68
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available