M21T (p.Met21Thr) variant of CYP19A1 (Aromatase)
M21T (p.Met21Thr) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
M21T (p.Met21Thr) variant details
- p.Met21Thr
- ESP rs145167479
- ExAC rs145167479
- TOPMed rs145167479
- gnomAD rs145167479
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.18
- CADD 18.10
- PolyPhen-2 0.02
- SIFT 0.20
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available