L37S (p.Leu37Ser) variant of CYP19A1 (Aromatase)
L37S (p.Leu37Ser) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
L37S (p.Leu37Ser) variant details
- p.Leu37Ser
- gnomAD rs1275171739
- Missense
- Variant Prioritization Score for Impact Estimate 0.461
- REVEL 0.36
- CADD 23.00
- PolyPhen-2 0.15
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available