K119R (p.Lys119Arg) variant of CYP19A1 (Aromatase)
K119R (p.Lys119Arg) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
K119R (p.Lys119Arg) variant details
- p.Lys119Arg
- TOPMed rs1328580070
- gnomAD rs1328580070
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.22
- CADD 22.00
- PolyPhen-2 0.03
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available