K119Q (p.Lys119Gln) variant of CYP19A1 (Aromatase)
K119Q (p.Lys119Gln) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
K119Q (p.Lys119Gln) variant details
- p.Lys119Gln
- gnomAD rs1443121773
- Missense
- Variant Prioritization Score for Impact Estimate 0.393
- REVEL 0.35
- CADD 23.80
- PolyPhen-2 0.08
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available