I13M (p.Ile13Met) variant of CYP19A1 (Aromatase)
I13M (p.Ile13Met) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
I13M (p.Ile13Met) variant details
- p.Ile13Met
- ExAC rs774053181
- gnomAD rs774053181
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.17
- CADD 19.70
- PolyPhen-2 0.20
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available