I132N (p.Ile132Asn) variant of CYP19A1 (Aromatase)
I132N (p.Ile132Asn) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
I132N (p.Ile132Asn) variant details
- p.Ile132Asn
- ESP rs371077463
- ExAC rs371077463
- TOPMed rs371077463
- gnomAD rs371077463
- Missense
- Variant Prioritization Score for Impact Estimate 0.685
- REVEL 0.70
- CADD 28.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 0.00012)
- Structural context available