H10R (p.His10Arg) variant of CYP19A1 (Aromatase)
H10R (p.His10Arg) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
H10R (p.His10Arg) variant details
- p.His10Arg
- ExAC rs752399730
- TOPMed rs752399730
- gnomAD rs752399730
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.30
- CADD 16.70
- PolyPhen-2 0.04
- SIFT 0.09
- Most common in the Ashkenazi Jewish population (allele frequency 0.00029)
- Structural context available