G131S (p.Gly131Ser) variant of CYP19A1 (Aromatase)
G131S (p.Gly131Ser) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
G131S (p.Gly131Ser) variant details
- p.Gly131Ser
- TOPMed rs1033623088
- gnomAD rs1033623088
- Missense
- Variant Prioritization Score for Impact Estimate 0.737
- REVEL 0.70
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available