F84L (p.Phe84Leu) variant of CYP19A1 (Aromatase)
F84L (p.Phe84Leu) in CYP19A1 (Aromatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
F84L (p.Phe84Leu) variant details
- p.Phe84Leu
- TOPMed rs1446833092
- gnomAD rs1446833092
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.21
- CADD 21.80
- PolyPhen-2 0.12
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available