Y27S (p.Tyr27Ser) variant of CYP17A1 (P05093)
Y27S (p.Tyr27Ser) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
Y27S (p.Tyr27Ser) variant details
- p.Tyr27Ser
- cosmic curated COSV64004
- ExAC rs757251521
- gnomAD rs757251521
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.14
- CADD 16.10
- PolyPhen-2 0.05
- SIFT 0.22
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available