V85L (p.Val85Leu) variant of CYP17A1 (P05093)
V85L (p.Val85Leu) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
V85L (p.Val85Leu) variant details
- p.Val85Leu
- TOPMed rs1844172932
- Missense
- Variant Prioritization Score for Impact Estimate 0.438
- REVEL 0.47
- CADD 23.30
- PolyPhen-2 0.52
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available