T70A (p.Thr70Ala) variant of CYP17A1 (P05093)
T70A (p.Thr70Ala) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
T70A (p.Thr70Ala) variant details
- p.Thr70Ala
- TOPMed rs908864807
- gnomAD rs908864807
- Missense
- Variant Prioritization Score for Impact Estimate 0.0948
- REVEL 0.12
- CADD 0.18
- PolyPhen-2 0.07
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available