T159A (p.Thr159Ala) variant of CYP17A1 (P05093)
T159A (p.Thr159Ala) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
T159A (p.Thr159Ala) variant details
- p.Thr159Ala
- ExAC rs769287572
- gnomAD rs769287572
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.02
- CADD 10.80
- PolyPhen-2 0.01
- SIFT 0.84
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available