R45K (p.Arg45Lys) variant of CYP17A1 (P05093)
R45K (p.Arg45Lys) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
R45K (p.Arg45Lys) variant details
- p.Arg45Lys
- TOPMed rs1844175591
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.11
- CADD 12.50
- PolyPhen-2 0.03
- SIFT 0.90
- Population evidence available
- Structural context available