R21S (p.Arg21Ser) variant of CYP17A1 (P05093)
R21S (p.Arg21Ser) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
R21S (p.Arg21Ser) variant details
- p.Arg21Ser
- TOPMed rs1354556683
- gnomAD rs1354556683
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- REVEL 0.17
- CADD 11.50
- PolyPhen-2 0.06
- SIFT 0.18
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available