R125* (p.Arg125Ter) variant of CYP17A1 (P05093)
R125* (p.Arg125Ter) in CYP17A1 (P05093) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
R125* (p.Arg125Ter) variant details
- p.Arg125Ter
- NCI-TCGA Cosmic COSV1008
- cosmic curated COSV10088
- TOPMed rs1844147281
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.492
- CADD 36.00
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available