P434L (p.Pro434Leu) variant of CYP17A1 (P05093)

P434L (p.Pro434Leu) in CYP17A1 (P05093) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Deficiency of steroid 17-alpha-monooxygenase. The record also includes structural context.

P434L (p.Pro434Leu) variant details