P41T (p.Pro41Thr) variant of CYP17A1 (P05093)
P41T (p.Pro41Thr) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
P41T (p.Pro41Thr) variant details
- p.Pro41Thr
- ExAC rs774295656
- gnomAD rs774295656
- Missense
- Variant Prioritization Score for Impact Estimate 0.549
- REVEL 0.38
- CADD 25.00
- PolyPhen-2 0.95
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available