P23L (p.Pro23Leu) variant of CYP17A1 (P05093)
P23L (p.Pro23Leu) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
P23L (p.Pro23Leu) variant details
- p.Pro23Leu
- ESP rs368405367
- TOPMed rs368405367
- gnomAD rs368405367
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.06
- CADD 5.46
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available