L86I (p.Leu86Ile) variant of CYP17A1 (P05093)
L86I (p.Leu86Ile) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
L86I (p.Leu86Ile) variant details
- p.Leu86Ile
- gnomAD rs1844172806
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- REVEL 0.54
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available