L86F (p.Leu86Phe) variant of CYP17A1 (P05093)
L86F (p.Leu86Phe) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
L86F (p.Leu86Phe) variant details
- p.Leu86Phe
- gnomAD rs1844172806
- Missense
- Variant Prioritization Score for Impact Estimate 0.638
- REVEL 0.66
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available