L36R (p.Leu36Arg) variant of CYP17A1 (P05093)
L36R (p.Leu36Arg) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
L36R (p.Leu36Arg) variant details
- p.Leu36Arg
- ExAC rs766687468
- gnomAD rs766687468
- Missense
- Variant Prioritization Score for Impact Estimate 0.656
- REVEL 0.67
- CADD 25.00
- PolyPhen-2 0.83
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available