L15W (p.Leu15Trp) variant of CYP17A1 (P05093)
L15W (p.Leu15Trp) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
L15W (p.Leu15Trp) variant details
- p.Leu15Trp
- TOPMed rs1844177977
- gnomAD rs1844177977
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- REVEL 0.24
- CADD 16.80
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available