L10P (p.Leu10Pro) variant of CYP17A1 (P05093)
L10P (p.Leu10Pro) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
L10P (p.Leu10Pro) variant details
- p.Leu10Pro
- ExAC rs779723871
- gnomAD rs779723871
- Missense
- Variant Prioritization Score for Impact Estimate 0.577
- REVEL 0.54
- CADD 23.90
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available