L102P (p.Leu102Pro) variant of CYP17A1 (P05093)
L102P (p.Leu102Pro) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
L102P (p.Leu102Pro) variant details
- p.Leu102Pro
- ExAC rs769319989
- gnomAD rs769319989
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.41
- CADD 22.60
- PolyPhen-2 0.81
- SIFT 0.06
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available