K83R (p.Lys83Arg) variant of CYP17A1 (P05093)
K83R (p.Lys83Arg) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
K83R (p.Lys83Arg) variant details
- p.Lys83Arg
- ExAC rs776580666
- TOPMed rs776580666
- gnomAD rs776580666
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.16
- CADD 15.30
- PolyPhen-2 0.16
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available