K59I (p.Lys59Ile) variant of CYP17A1 (P05093)
K59I (p.Lys59Ile) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
K59I (p.Lys59Ile) variant details
- p.Lys59Ile
- TOPMed rs1465948613
- gnomAD rs1465948613
- Missense
- Variant Prioritization Score for Impact Estimate 0.585
- REVEL 0.67
- CADD 24.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available