I145T (p.Ile145Thr) variant of CYP17A1 (P05093)
I145T (p.Ile145Thr) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
I145T (p.Ile145Thr) variant details
- p.Ile145Thr
- Ensembl rs1590204077
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.26
- CADD 25.40
- PolyPhen-2 0.46
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available